纳米乳液体系对白藜芦醇促进渗透性的研究
关键词：纳米乳液；添加剂；稳定性；渗透
Influence of nanoemulsions on the penetrability of resveratrol
Abstract：The main topic of the effects of additives on preparation and shea butter to its particle size nanoemulsion, including the impact of different types of oils, ionic surfactants, moisturizers and rheology modifiers. And the effects of nano-emulsion particle size effect of resveratrol in the penetration and permeability of nano-emulsions containing different levels of resveratrol. Also studied particle stability and the stability of nano-emulsions resveratrol. Experimental results show that nano-emulsion of vegetable oils affect a smaller particle size, and synthetic oils in liquid oil nanoemulsion particle size effects on small diameter solid fats increase significantly so. Anionic and cationic surface active AES 1631 enables enhanced charging system, but also to make the particle size increases. Humectant glycerol and 1,3-butanediol impact on nano-emulsion system larger particle size, but a small effect on the PDI values. Join rheology modifier makes the system size and PDI values were significantly increased. The results also show that the poor low temperature stability of nano-emulsions, but better temperature stability. Stability of resveratrol are better.With resveratrol and resveratrol nanoemulsion lotion penetrate ordinary compared to the permeability of nano-emulsion better.
Keywords: nano-emulsions; preparation method; stability; Transdermal absorption
目录
1.绪论 1
1.1 纳米乳液的概述 1
1.1.1 纳米乳液的含义 1
1.1.2 纳米乳液的特性 1
1.1.3 纳米乳液的结构测定 1
1.2 纳米乳液的制备 2
1.2.1 机械法制备纳米乳剂 2
1.2.2 低能乳化法 2
1.3 纳米乳液的稳定性考察 2
1.3.1 过处理问题( over- processing ) 3
1.3.2 奥氏熟化现象(Ostwald ripening) 3
1.4 纳米乳液的应用 3
1.4.1 纳米乳液在化妆品中的应用 3
1.4.2 纳米乳液技术用于开发含高活性成分的纳米乳液 4
1.5 白藜芦醇在化妆品中的应用 4
1.5.1 白藜芦醇具有明显的抗衰老功效 4
1.5.2 白藜芦醇的美白功效 4
1.6 本课题的研究意义 4
2实验内容 6
2.1 实验原料与设备 6
2.1.1 实验原料： 6
2.1.2 实验所用设备： 6
2.2 实验方法 7
2.2.1 纳米乳液的制备方法 7
2.2.2 纳米乳液粒径分析方法 8