PIT乳化法的影响因素研究
毕业论文关键词：O/W 纳米乳液；相转变温度法；低能乳化法 Study of the Influence Factors of Phase Inversion Temperature (PIT) Emulsification Abstract:This subject mainly research the Influence Factors of using Phase Inversion Temperature (PIT) Emulsification to prepare nano-emulsion.First with cetyl stearyl alcohol polyether-12(B1) and cetyl stearyl alcohol polyether-20(B2) do emulsifier,cetostearyl alcohol do solid fat,myristic acid isopropyl ester do liquid oil and glycerol as a moisturizer,Glydant Plus Liquid as preservative,allowance for the water to finish the initial formula.Then by changing the ratio of different emulsifiers in the initial formulation and transforming the kinds of liquid oil of the formul explores a formula that can happen phase inversion and finally the emulsion particle size is of 50-200nm. Based on the formula that has explored and through the experiment we obtain how the different ratio of emulsifier and different content of hexadecanoic acid isooctyl ester,different types of polyol and different glycerol content to influence that using Phase Inversion Temperature (PIT) Emulsification to prepare nano-emulsion.In this subject,the main characterization methods is to measure the nanometer particle size of emulsion and PDI value, the absolute value of Zeta potential and the viscosity of nano-emulsion by using different formulas.The experimental results show that the size of nano-emulsion and PDI value,the absolute value of Zeta potential size,the viscosity of the nano-emulsion which was prepared by Phase Inversion Temperature(PIT) Emulsification is relevant to the ratio of emulsifier, the different content of hexadecanoic acid isooctyl ester and different concentrations of glycerol of different formulas and presents the obvious regularity.By the experiment conclusion can speculate that the intermiscibility of multivariate alcohol and oil with emulsifier is the biggest influence factor that using Phase Inversion Temperature(PIT) Emulsification to prepare nano-emulsion.
Keywords: O/W nano-emulsions；phase inversion temperature method (PIT)；low energy emulsification
目 录
1 前言 ... 1
1.1 纳米乳液概述 . 1
1.1.1 纳米乳液的定义 .. 1
1.1.2 纳米乳液的性能特征 .. 1
1.2 纳米乳液的制备 . 1
1.2.1 高能乳化法制备纳米乳液 .. 1
1.2.1.1 高压均质法 ... 1
1.2.1.2 超声乳化法 ... 1
1.2.1.3 微射流乳化法 ... 1